Hyacyst® (sodium hyaluronate)

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Hyacyst® (sodium hyaluronate) is a bladder instillation indicated for the temporary replenishment of the GAG layer in the following bladder conditions; interstitial cystitis (IC), painful bladder syndrome (PBS), haemorrhagic cystitis, recurrent bacterial cystitis, radiation induced cystitis and chemotherapy induced cystitis.

Hyacyst® (sodium hyaluronate) is available in strengths of 40mg/50ml and 120mg/50ml which are supplied as Pre-Filled Syringes (PFS) or Vials. Hyacyst® PFS packs include a catheter adaptor to enable Hyacyst® PFS to be used with a wide variety of available catheters, making them suitable for self-instillation at home.

Hyacyst® (sodium hyaluronate) is approved for prescribing in the Community on FP10 prescriptions in the UK.

Hyacyst® (sodium hyaluronate) 40 PFS is the only sodium hyaluronate bladder instillation in a pre-filled syringe.

Hyacyst® (sodium hyaluronate) 120 PFS is a higher dose option when increased replenishment of the GAG layer is required.

In a 2014 randomised study, Hyacyst® (sodium hyaluronate) 120mg/50ml was proven to be as effective as combination treatment (iAluRil®) in reducing symptoms in patients with IC/PBS1.

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References:

  1. Gülpinar O et al. Clinical comparison of intravesical hyaluronic acid and hyaluronic acid-chondroitin sulphate therapy for patients with bladder pain syndrome/interstitial cystitis. Can Urol Assoc J 2014;8(9-10):e610-4’
Reporting of side effects. If you get any side effects, talk to your doctor, pharmacist or nurse. This includes any possible side effects not listed in the package leaflet. You can also report side effects directly via the Yellow Card Scheme at www.mhra.gov.uk/yellowcard. By reporting side effects you can help provide more information on the safety of this medicine. Adverse events should also be reported to Syner-Med (Pharmaceutical Products) Limited. Tel. +44 020 8655 6380

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