Hyacyst® (sodium hyaluronate) is a bladder instillation indicated for the temporary replenishment of the GAG layer in the following bladder conditions; interstitial cystitis (IC), painful bladder syndrome (PBS), haemorrhagic cystitis, recurrent bacterial cystitis, radiation induced cystitis and chemotherapy induced cystitis.
Hyacyst® (sodium hyaluronate) is available in strengths of 40mg/50ml and 120mg/50ml which are supplied as Pre-Filled Syringes (PFS) or Vials. Hyacyst® PFS packs include a catheter adaptor to enable Hyacyst® PFS to be used with a wide variety of available catheters, making them suitable for self-instillation at home.
Hyacyst® (sodium hyaluronate) is approved for prescribing in the Community on FP10 prescriptions in the UK.
Hyacyst® (sodium hyaluronate) 40 PFS is the only sodium hyaluronate bladder instillation in a pre-filled syringe.
Hyacyst® (sodium hyaluronate) 120 PFS is a higher dose option when increased replenishment of the GAG layer is required.
In a 2014 randomised study, Hyacyst® (sodium hyaluronate) 120mg/50ml was proven to be as effective as combination treatment (iAluRil®) in reducing symptoms in patients with IC/PBS1.
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| Attachment | Size |
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 Hyacyst® (sodium hyaluronate) Patient Leaflet | 716.98 KB |
| Hyacyst® (sodium hyaluronate) Vial IFU | 120.04 KB |
| Hyacyst® (sodium hyaluronate) Syringe IFU | 118.68 KB |
References:
- Gülpinar O et al. Clinical comparison of intravesical hyaluronic acid and hyaluronic acid-chondroitin sulphate therapy for patients with bladder pain syndrome/interstitial cystitis. Can Urol Assoc J 2014;8(9-10):e610-4’